HCN2 antibody

Catalog No. ABIN7115163

This anti-HCN2 antibody is a Rabbit Polyclonal antibody detecting HCN2 in WB and ELISA. Suitable for Human, Rat and Mouse.

Quick Overview for HCN2 antibody (ABIN7115163)

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HCN2 Antibody

Purpose: HCN2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: Extracellular domain

Immunogen: hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HCN2

Target: HCN2 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 2 (HCN2))

Alternative Name: HCN2

Background:

Synonyms: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2|Brain cyclic nucleotide-gated channel 2 (BCNG-2)|HCN2|BCNG2

Background: Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart(If) and in neurons(Ih). Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH , acidic pH shifts the activation to more negative voltages(By similarity).

Molecular Weight: 97 kDa

Gene ID: 610

UniProt: Q9UL51