Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (AA 30-206) antibody

Catalog No. ABIN7115187

The Rabbit Polyclonal anti-Peptidyl-tRNA Hydrolase ICT1, Mitochondrial antibody (ABIN7115187) specifically detects Peptidyl-tRNA Hydrolase ICT1, Mitochondrial in ELISA, WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Peptidyl-tRNA Hydrolase ICT1, Mitochondrial (AA 30-206) antibody (ABIN7115187)

Target: Peptidyl-tRNA Hydrolase ICT1, Mitochondrial

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 30-206

Purpose: MRPL58 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 30-206aa

Immunogen: immature colon carcinoma transcript 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: Peptidyl-tRNA Hydrolase ICT1, Mitochondrial

Alternative Name: MRPL58

Background:

Synonyms: Large ribosomal subunit protein mL62|39S ribosomal protein L58, mitochondrial (MRP-L58)|Digestion substraction 1 (DS-1)|Immature colon carcinoma transcript 1 protein|Peptidyl-tRNA hydrolase ICT1, mitochondrial|MRPL58|DS1|ICT1

Background: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.This antibody is a rabbit polyclonal antibody raised against a full-length human ICT1 protein

Molecular Weight: 21-24 kDa

UniProt: Q14197