IGSF8 antibody (AA 28-350)

Catalog No. ABIN7115202

This anti-IGSF8 antibody is a Rabbit Polyclonal antibody detecting IGSF8 in WB, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for IGSF8 antibody (AA 28-350) (ABIN7115202)

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGSF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-IGSF8 Antibody

Binding Specificity: AA 28-350

Purpose: IGSF8 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 28-350aa

Immunogen: immunoglobulin superfamily, member 8

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IGSF8

Target: IGSF8 (Immunoglobulin Superfamily, Member 8 (IGSF8))

Alternative Name: IGSF8

Background:

Synonyms: Immunoglobulin superfamily member 8 (IgSF8)|CD81 partner 3|Glu-Trp-Ile EWI motif-containing protein 2 (EWI-2)|Keratinocytes-associated transmembrane protein 4 (KCT-4)|LIR-D1|Prostaglandin regulatory-like protein (PGRL)|IGSF8|CD81P3|EWI2|KCT4

Background: May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.

Molecular Weight: 70 kDa

Gene ID: 93185

UniProt: Q969P0