ING2 antibody

Catalog No. ABIN7115234

The Rabbit Polyclonal anti-ING2 antibody is suitable to detect ING2 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IHC and IP.

Quick Overview for ING2 antibody (ABIN7115234)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ING2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-ING2 Antibody

Purpose: ING2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: inhibitor of growth family, member 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Alternative Name: ING2

Background:

Synonyms: Inhibitor of growth protein 2|Inhibitor of growth 1-like protein (ING1Lp)|p32|p33ING2|ING2|ING1L

Background: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides(PtdInsPs).

Molecular Weight: 33 kDa

Gene ID: 3622

UniProt: Q9H160

Pathways: Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling