IRF2BP1 antibody

Catalog No. ABIN7115363

The Rabbit Polyclonal anti-IRF2BP1 antibody is suitable to detect IRF2BP1 in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC, IF and IP.

Quick Overview for IRF2BP1 antibody (ABIN7115363)

Target: IRF2BP1 (Interferon Regulatory Factor 2 Binding Protein 1 (IRF2BP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2BP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-IRF2BP1 Antibody

Purpose: IRF2BP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interferon regulatory factor 2 binding protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IRF2BP1

Target: IRF2BP1 (Interferon Regulatory Factor 2 Binding Protein 1 (IRF2BP1))

Alternative Name: IRF2BP1

Background:

Synonyms: Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1, IRF-2BP1)|Probable E3 ubiquitin-protein ligase IRF2BP1|Probable RING-type E3 ubiquitin transferase IRF2BP1|IRF2BP1

Background: Acts as a transcriptional corepressor in a IRF2-dependent manner, this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.

Molecular Weight: 62-72 kDa

Gene ID: 26145

UniProt: Q8IU81