PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
IL1RL2
(Interleukin 1 Receptor-Like 2 (IL1RL2))
Alternative Name
IL1RL2
Background
Synonyms:IL 1Rrp2, IL1R rp2, IL1RL2, IL1RRP2, interleukin 1 receptor like 2 Background:Receptor for interleukin-36(IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways(By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response, it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.