IL22RA2 antibody (AA 1-263)

Catalog No. ABIN7115449

This Mouse Monoclonal antibody specifically detects IL22RA2 in WB, ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for IL22RA2 antibody (AA 1-263) (ABIN7115449)

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL22RA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 8C11

Product Details anti-IL22RA2 Antibody

Binding Specificity: AA 1-263

Purpose: IL22RA2 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-263aa

Immunogen: interleukin 22 receptor, alpha 2

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL22RA2

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Alternative Name: IL22RA2

Background:

Synonyms: Interleukin-22 receptor subunit alpha-2 (IL-22 receptor subunit alpha-2, IL-22R-alpha-2, IL-22RA2)|Cytokine receptor class-II member 10|Cytokine receptor family 2 member 10 (CRF2-10)|Cytokine receptor family type 2, soluble 1 (CRF2-S1)|Interleukin-22-binding protein (IL-22BP, IL22BP)|ZcytoR16|IL22RA2

Background: Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22(in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses. Isoform 1 may play a role in establishing and maintaining successful pregnancy.

Molecular Weight: 35 kDa

Gene ID: 116379

UniProt: Q969J5