IL-37 antibody (AA 1-218)

Catalog No. ABIN7115463

The Mouse Monoclonal anti-IL-37 antibody (Clone 6A2) (ABIN7115463) specifically detects IL-37 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for IL-37 antibody (AA 1-218) (ABIN7115463)

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-37 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 6A2

Product Details anti-IL-37 Antibody

Binding Specificity: AA 1-218

Purpose: IL37 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-218aa

Immunogen: interleukin 1 family, member 7(zeta)

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:10000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Alternative Name: IL37

Background:

Synonyms: Interleukin-37 (IL-37)|FIL1 zeta|IL-1X|Interleukin-1 family member 7 (IL-1F7)|Interleukin-1 homolog 4 (IL-1H, IL-1H4)|Interleukin-1 zeta (IL-1 zeta)|Interleukin-1-related protein (IL-1RP1)|IL37|FIL1Z|IL1F7|IL1H4|IL1RP1

Background: Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Molecular Weight: 30 kDa

Gene ID: 27178

UniProt: Q9NZH6