KATNB1 antibody

Catalog No. ABIN7115579

The Rabbit Polyclonal anti-KATNB1 antibody has been validated for WB, ELISA and IP. It is suitable to detect KATNB1 in samples from Human, Mouse and Rat.

Quick Overview for KATNB1 antibody (ABIN7115579)

Target: KATNB1 (Katanin P80 (WD Repeat Containing) Subunit B 1 (KATNB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KATNB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-KATNB1 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: katanin p80(WD repeat containing) subunit B 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for KATNB1

Target: KATNB1 (Katanin P80 (WD Repeat Containing) Subunit B 1 (KATNB1))

Alternative Name: KATNB1

Background: Synonyms:KAT, Katanin p80 subunit B1, KATNB1, p80 katanin Background:Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.

Molecular Weight: 72-80 kDa

Gene ID: 10300

UniProt: Q9BVA0

Pathways: Microtubule Dynamics