KCNIP4 antibody

Catalog No. ABIN7115740

This Rabbit Polyclonal antibody specifically detects KCNIP4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for KCNIP4 antibody (ABIN7115740)

Target: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNIP4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNIP4 Antibody

Purpose: KCNIP4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Kv channel interacting protein 4

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for KCNIP4

Target: KCNIP4 (Kv Channel Interacting Protein 4 (KCNIP4))

Alternative Name: KCNIP4

Background:

Synonyms: Kv channel-interacting protein 4 (KChIP4)|A-type potassium channel modulatory protein 4|Calsenilin-like protein|Potassium channel-interacting protein 4|KCNIP4|CALP|KCHIP4

Background: Regulatory subunit of Kv4/D(Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner(PubMed:11847232, PubMed:18957440, PubMed:23576435). Modulates KCND3/Kv4.3 currents(PubMed:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane(PubMed:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.

Molecular Weight: 29 kDa

Gene ID: 80333

UniProt: Q6PIL6