LAS1L antibody

Catalog No. ABIN7115770

This Rabbit Polyclonal antibody specifically detects LAS1L in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LAS1L antibody (ABIN7115770)

Target: LAS1L (LAS1-Like (LAS1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAS1L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-LAS1L Antibody

Purpose: LAS1L antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: LAS1-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for LAS1L

Target: LAS1L (LAS1-Like (LAS1L))

Alternative Name: LAS1L

Background:

Synonyms: Ribosomal biogenesis protein LAS1L|Endoribonuclease LAS1L|Protein LAS1 homolog|LAS1L

Background: Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Molecular Weight: 83 kDa, 70-75 kDa

Gene ID: 81887

UniProt: Q9Y4W2