LRRC8C antibody

Catalog No. ABIN7115813

The Rabbit Polyclonal anti-LRRC8C antibody has been validated for ELISA, IF and IHC. It is suitable to detect LRRC8C in samples from Human, Mouse and Rat.

Quick Overview for LRRC8C antibody (ABIN7115813)

Target: LRRC8C (Leucine Rich Repeat Containing 8 Family, Member C (LRRC8C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8C antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-LRRC8C Antibody

Purpose: LRRC8C antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: leucine rich repeat containing 8 family, member C

Isotype: IgG

Application Details

Application Notes: IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for LRRC8C

Target: LRRC8C (Leucine Rich Repeat Containing 8 Family, Member C (LRRC8C))

Alternative Name: LRRC8C

Background:

Synonyms: Volume-regulated anion channel subunit LRRC8C|Factor for adipocyte differentiation 158|Leucine-rich repeat-containing protein 8C|LRRC8C|AD158|FAD158

Background: Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition.

Gene ID: 84230

UniProt: Q8TDW0