MBL2 antibody (AA 21-248)

Catalog No. ABIN7116044

The Rabbit Polyclonal anti-MBL2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect MBL2 in samples from Human, Mouse and Rat.

Quick Overview for MBL2 antibody (AA 21-248) (ABIN7116044)

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MBL2 Antibody

Binding Specificity: AA 21-248

Purpose: MBL2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 21-248aa

Immunogen: mannose-binding lectin (protein C) 2, soluble (opsonic defect)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2

Background:

Synonyms: Mannose-binding protein C (MBP-C)|Collectin-1|MBP1|Mannan-binding protein|Mannose-binding lectin|MBL2|COLEC1|MBL

Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Molecular Weight: 30 kDa

Gene ID: 4153

UniProt: P11226

Pathways: Complement System, Positive Regulation of Immune Effector Process