MBL2 antibody (N-Term)

Catalog No. ABIN6259103

Product Details anti-MBL2 Antibody

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: MBL2 Antibody detects endogenous levels of total MBL2.

Predicted Reactivity: Pig,Bovine,Sheep,Rabbit,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MBL2, corresponding to a region within N-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2 (MBL2 Products)

Synonyms: COLEC1 antibody, HSMBPC antibody, MBL antibody, MBL2D antibody, MBP antibody, MBP-C antibody, MBP1 antibody, MBPD antibody, pMBP-27 antibody, mbl2 antibody, MBL1 antibody, cMBl antibody, collectin antibody, Ab2-001 antibody, Ab2-011 antibody, L-MBP antibody, MBL-C antibody, COLEC2 antibody, mbl antibody, etID42583.2 antibody, fb68b07 antibody, hbl3 antibody, wu:fb68b07 antibody, zgc:109836 antibody, mannose binding lectin 2 antibody, Mannose-binding protein C antibody, mannose-binding lectin (protein C) 2, soluble antibody, mannose-binding lectin (protein C) 2 antibody, mannose-binding lectin family member 3, pseudogene antibody, MBL2 antibody, mbl2 antibody, Mbl2 antibody, MBL3P antibody

Background:

Description: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.

Gene: MBL2

Molecular Weight: 27 kDa

Gene ID: 4153

UniProt: P11226

Pathways: Complement System, Positive Regulation of Immune Effector Process