MGAT5B antibody

Catalog No. ABIN7116053

The Rabbit Polyclonal anti-MGAT5B antibody is suitable to detect MGAT5B in samples from Human and Rat. It has been validated for WB, ELISA and IP.

Quick Overview for MGAT5B antibody (ABIN7116053)

Target: MGAT5B (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase, Isozyme B (MGAT5B))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT5B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-MGAT5B Antibody

Purpose: MGAT5B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mannosyl(alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MGAT5B

Target: MGAT5B (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,6-N-Acetyl-Glucosaminyltransferase, Isozyme B (MGAT5B))

Alternative Name: MGAT5B

Background:

Synonyms: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B|Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B|GlcNAc-T Vb (GNT-Vb, hGnTVb)|Mannoside acetylglucosaminyltransferase 5B|N-acetylglucosaminyl-transferase Vb|N-acetylglucosaminyltransferase IX (GNT-IX)|MGAT5B|KIAA2008

Background: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine(GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3-and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.

Molecular Weight: 89-100 kDa

Gene ID: 146664

UniProt: Q3V5L5