MED12L antibody

Catalog No. ABIN7116118

This Rabbit Polyclonal antibody specifically detects MED12L in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MED12L antibody (ABIN7116118)

Target: MED12L (Mediator Complex Subunit 12-Like (MED12L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED12L antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MED12L Antibody

Purpose: MED12L antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mediator complex subunit 12-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MED12L

Target: MED12L (Mediator Complex Subunit 12-Like (MED12L))

Alternative Name: MED12L

Background:

Synonyms: Mediator of RNA polymerase II transcription subunit 12-like protein|Mediator complex subunit 12-like protein|Thyroid hormone receptor-associated-like protein|Trinucleotide repeat-containing gene 11 protein-like|MED12L|KIAA1635|TNRC11L|TRALP|TRALPUSH

Background: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors(By similarity).

Molecular Weight: 260-280 kDa

Gene ID: 116931

UniProt: Q86YW9