MEX3C antibody

Catalog No. ABIN7116273

The Rabbit Polyclonal anti-MEX3C antibody (ABIN7116273) specifically detects MEX3C in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for MEX3C antibody (ABIN7116273)

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEX3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MEX3C Antibody

Purpose: MEX3C antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mex-3 homolog C(C. elegans)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MEX3C

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Alternative Name: MEX3C

Background:

Synonyms: RNA-binding E3 ubiquitin-protein ligase MEX3C|RING finger and KH domain-containing protein 2|RING finger protein 194|RING-type E3 ubiquitin transferase MEX3C|MEX3C|RKHD2|RNF194

Background: E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

Molecular Weight: 69 kDa

Gene ID: 51320

UniProt: Q5U5Q3