MICALL2 antibody

Catalog No. ABIN7116277

This Rabbit Polyclonal antibody specifically detects MICALL2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for MICALL2 antibody (ABIN7116277)

Target: MICALL2 (MICAL-Like 2 (MICALL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MICALL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MICALL2 Antibody

Purpose: MICALL2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: MICAL-like 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MICALL2

Target: MICALL2 (MICAL-Like 2 (MICALL2))

Alternative Name: MICALL2

Background:

Synonyms: MICAL-like protein 2|Junctional Rab13-binding protein|Molecule interacting with CasL-like 2 (MICAL-L2)|MICALL2|JRAB

Background: Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth(By similarity).

Molecular Weight: 109 kDa

Gene ID: 79778

UniProt: Q8IY33