MCRS1 antibody

Catalog No. ABIN7116283

This Rabbit Polyclonal antibody specifically detects MCRS1 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for MCRS1 antibody (ABIN7116283)

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCRS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MCRS1 Antibody

Purpose: MCRS1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: microspherule protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MCRS1

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Alternative Name: MCRS1

Background:

Synonyms: Microspherule protein 1|58 kDa microspherule protein|Cell cycle-regulated factor p78|INO80 complex subunit J|MCRS2|MCRS1|INO80Q|MSP58

Background: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus(PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues(PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity(PubMed:15044100). Binds to G-quadruplex structures in mRNA(PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U)(PubMed:16571602).

Molecular Weight: 55 kDa

Gene ID: 10445

UniProt: Q96EZ8