MCRS1 antibody

Catalog No. ABIN7116284

The Mouse Monoclonal anti-MCRS1 antibody is suitable to detect MCRS1 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for MCRS1 antibody (ABIN7116284)

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This MCRS1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Clone: 5G3

Product Details anti-MCRS1 Antibody

Purpose: MCRS1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: microspherule protein 1

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MCRS1

Target: MCRS1 (Microspherule Protein 1 (MCRS1))

Alternative Name: MCRS1

Background:

Synonyms: Microspherule protein 1|58 kDa microspherule protein|Cell cycle-regulated factor p78|INO80 complex subunit J|MCRS2|MCRS1|INO80Q|MSP58

Background: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus(PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues(PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity(PubMed:15044100). Binds to G-quadruplex structures in mRNA(PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U)(PubMed:16571602).

Molecular Weight: 55 kDa

Gene ID: 10445

UniProt: Q96EZ8