MCM10 antibody

Catalog No. ABIN7116316

This Rabbit Polyclonal antibody specifically detects MCM10 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for MCM10 antibody (ABIN7116316)

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCM10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MCM10 Antibody

Purpose: MCM10 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: minichromosome maintenance complex component 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MCM10

Target: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Alternative Name: MCM10

Background:

Synonyms: Protein MCM10 homolog (HsMCM10)|MCM10

Background: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication. Key effector of the RBBP6 and ZBTB38-mediated regulation of DNA-replication and common fragile sites stability, acts as a direct target of transcriptional repression by ZBTB38(PubMed:24726359).

Molecular Weight: 97-105 kDa

Gene ID: 55388

UniProt: Q7L590

Pathways: Mitotic G1-G1/S Phases, DNA Replication