MRPL28 antibody

Catalog No. ABIN7116352

This Rabbit Polyclonal antibody specifically detects MRPL28 in WB, ELISA, IHC, IF and IP. It exhibits reactivity toward Human and Rat.

Quick Overview for MRPL28 antibody (ABIN7116352)

Target: MRPL28 (Mitochondrial Ribosomal Protein L28 (MRPL28))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL28 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-MRPL28 Antibody

Purpose: MRPL28 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mitochondrial ribosomal protein L28

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100, IP: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MRPL28

Target: MRPL28 (Mitochondrial Ribosomal Protein L28 (MRPL28))

Alternative Name: MRPL28

Background:

Synonyms: Large ribosomal subunit protein bL28m|39S ribosomal protein L28, mitochondrial (L28mt, MRP-L28)|Melanoma antigen p15|Melanoma-associated antigen recognized by T-lymphocytes|MRPL28|MAAT1

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.

Molecular Weight: 30 kDa

Gene ID: 10573

UniProt: Q13084

Pathways: Mitotic G1-G1/S Phases