MRPS22 antibody

Catalog No. ABIN7116380

The Rabbit Polyclonal anti-MRPS22 antibody has been validated for WB, ELISA and IHC. It is suitable to detect MRPS22 in samples from Human and Mouse.

Quick Overview for MRPS22 antibody (ABIN7116380)

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-MRPS22 Antibody

Purpose: MRPS22 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mitochondrial ribosomal protein S22

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MRPS22

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Alternative Name: MRPS22

Background:

Synonyms: Small ribosomal subunit protein mS22|28S ribosomal protein S22, mitochondrial (MRP-S22, S22mt)|MRPS22|C3orf5|RPMS22

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.

Molecular Weight: 41 kDa

Gene ID: 56945

UniProt: P82650