MRPS22 antibody (AA 231-280)

Catalog No. ABIN1535022

This Rabbit Polyclonal antibody specifically detects MRPS22 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Monkey, Cow and Hamster.

Quick Overview for MRPS22 antibody (AA 231-280) (ABIN1535022)

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Reactivity: Human, Monkey, Cow, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPS22 Antibody

Binding Specificity: AA 231-280

Purpose: MRP-S22 Antibody

Specificity: MRP-S22 Polyclonal Antibody detects endogenous levels of MRP-S22 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRPS22. AA range:231-280

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MRPS22

Target: MRPS22 (Mitochondrial Ribosomal Protein S22 (MRPS22))

Alternative Name: MRPS22

Background:

Synonyms: MRPS22, C3orf5, RPMS22, GK002, 28S ribosomal protein S22, mitochondrial, MRP-S22, S22mt

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene

Gene Name: MRPS22

Protein Name: 28S ribosomal protein S22 mitochondrial

Molecular Weight: 41 kDa

Gene ID: 56945

OMIM: 605810

UniProt: P82650