MALT1 antibody

Catalog No. ABIN7116527

The Mouse Monoclonal anti-MALT1 antibody has been validated for WB and ELISA. It is suitable to detect MALT1 in samples from Human.

Quick Overview for MALT1 antibody (ABIN7116527)

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MALT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 7A10

Product Details anti-MALT1 Antibody

Purpose: MALT1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: mucosa associated lymphoid tissue lymphoma translocation gene 1

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MALT1

Target: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Alternative Name: MALT1

Background:

Synonyms: Mucosa-associated lymphoid tissue lymphoma translocation protein 1|MALT lymphoma-associated translocation|Paracaspase|MALT1|MLT

Background: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Molecular Weight: 90 kDa

Gene ID: 10892

UniProt: Q9UDY8

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins