MPZL1 antibody

Catalog No. ABIN7116561

The Rabbit Polyclonal anti-MPZL1 antibody (ABIN7116561) specifically detects MPZL1 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MPZL1 antibody (ABIN7116561)

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MPZL1 Antibody

Purpose: MPZL1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: myelin protein zero-like 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MPZL1

Target: MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Alternative Name: MPZL1

Background:

Synonyms: Myelin protein zero-like protein 1|Protein zero-related|MPZL1|PZR

Background: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A(ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Molecular Weight: 16 kDa

Gene ID: 9019

UniProt: O95297