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MPZL1 antibody

This anti-MPZL1 antibody is a Rabbit Polyclonal antibody detecting MPZL1 in WB and ELISA. Suitable for Human, Mouse and Rat.
Catalog No. ABIN7116561

Quick Overview for MPZL1 antibody (ABIN7116561)

Target

See all MPZL1 Antibodies
MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

Reactivity

  • 25
  • 10
  • 10
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Human, Mouse, Rat

Host

  • 22
  • 3
Rabbit

Clonality

  • 25
Polyclonal

Conjugate

  • 14
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MPZL1 antibody is un-conjugated

Application

  • 13
  • 7
  • 5
  • 2
  • 1
Western Blotting (WB), ELISA
  • Purification

    Immunogen affinity purified

    Purity

    ≥95 % as determined by SDS-PAGE

    Immunogen

    myelin protein zero-like 1

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Expiry Date

    12 months
  • Target

    MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))

    Alternative Name

    MPZL1

    Background

    Synonyms:PZR Background:Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A(ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

    Molecular Weight

    16kd

    Gene ID

    9019

    UniProt

    O95297
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