MYO1E antibody
Quick Overview for MYO1E antibody (ABIN7116614)
Target
See all MYO1E AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- myosin IE
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Expiry Date
- 12 months
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- MYO1E (Myosin IE (MYO1E))
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Alternative Name
- MYO1E
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Background
- Synonyms:MYO1C Background:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14.
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Molecular Weight
- 127 kDa
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Gene ID
- 4643
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UniProt
- Q12965
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Pathways
- Platelet-derived growth Factor Receptor Signaling
Target
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