NKRF antibody

Catalog No. ABIN7116854

The Rabbit Polyclonal anti-NKRF antibody is suitable to detect NKRF in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IP.

Quick Overview for NKRF antibody (ABIN7116854)

Target: NKRF (NFKB Repressing Factor (NKRF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKRF antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-NKRF Antibody

Purpose: NKRF antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NFKB repressing factor

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NKRF

Target: NKRF (NFKB Repressing Factor (NKRF))

Alternative Name: NKRF

Background:

Synonyms: NF-kappa-B-repressing factor (NFkB-repressing factor, NRF)|Protein ITBA4|NKRF|ITBA4|NRF

Background: Interacts with a specific negative regulatory element(NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.

Molecular Weight: 100 kDa

Gene ID: 55922

UniProt: O15226