NME5 antibody

Catalog No. ABIN7116910

This Rabbit Polyclonal antibody specifically detects NME5 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NME5 antibody (ABIN7116910)

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-NME5 Antibody

Purpose: NME5 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: non-metastatic cells 5, protein expressed in(nucleoside-diphosphate kinase)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NME5

Target: NME5 (NME/NM23 Family Member 5 (NME5))

Alternative Name: NME5

Background:

Synonyms: Nucleoside diphosphate kinase homolog 5 (NDK-H 5, NDP kinase homolog 5)|Inhibitor of p53-induced apoptosis-beta (IPIA-beta)|Testis-specific nm23 homolog|nm23-H5|NME5

Background: Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species(By similarity).

Molecular Weight: 24 kDa

Gene ID: 8382

UniProt: P56597

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling