OSGEP antibody

Catalog No. ABIN7117095

The Rabbit Polyclonal anti-OSGEP antibody (ABIN7117095) specifically detects OSGEP in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for OSGEP antibody (ABIN7117095)

Target: OSGEP (O-Sialoglycoprotein Endopeptidase (OSGEP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSGEP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-OSGEP Antibody

Purpose: OSGEP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: O-sialoglycoprotein endopeptidase

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for OSGEP

Target: OSGEP (O-Sialoglycoprotein Endopeptidase (OSGEP))

Alternative Name: OSGEP

Background:

Synonyms: tRNA N6-adenosine threonylcarbamoyltransferase|N6-L-threonylcarbamoyladenine synthase (t(6)A synthase)|O-sialoglycoprotein endopeptidase (hOSGEP)|t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP|tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP|OSGEP|GCPL1

Background: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37(t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP(TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.

Molecular Weight: 36 kDa

Gene ID: 55644

UniProt: Q9NPF4