PBK antibody

Catalog No. ABIN7117269

This anti-PBK antibody is a Rabbit Polyclonal antibody detecting PBK in WB, ELISA, IHC, IF and FACS. Suitable for Human, Mouse and Rat.

Quick Overview for PBK antibody (ABIN7117269)

Target: PBK (PDZ Binding Kinase (PBK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PBK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PBK Antibody

Purpose: PBK antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PDZ binding kinase

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PBK

Target: PBK (PDZ Binding Kinase (PBK))

Alternative Name: PBK

Background:

Synonyms: Lymphokine-activated killer T-cell-originated protein kinase|Cancer/testis antigen 84 (CT84)|MAPKK-like protein kinase|Nori-3|PDZ-binding kinase|Spermatogenesis-related protein kinase (SPK)|T-LAK cell-originated protein kinase|PBK|TOPK

Background: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Molecular Weight: 36-40 kDa

Gene ID: 55872

UniProt: Q96KB5