PDZK1 antibody

Catalog No. ABIN7117270

This Rabbit Polyclonal antibody specifically detects PDZK1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDZK1 antibody (ABIN7117270)

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDZK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PDZK1 Antibody

Purpose: PDZK1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PDZ domain containing 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:20 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PDZK1

Target: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Alternative Name: PDZK1

Background:

Synonyms: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (NHERF-3)|CFTR-associated protein of 70 kDa|Na(+)/H(+) exchanger regulatory factor 3|Na/Pi cotransporter C-terminal-associated protein 1 (NaPi-Cap1)|PDZ domain-containing protein 1|Sodium-hydrogen exchanger regulatory factor 3|PDZK1|CAP70|NHERF3|PDZD1

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 67 kDa

Gene ID: 5174

UniProt: Q5T2W1