Pellino 1 antibody

Catalog No. ABIN7117275

The Rabbit Polyclonal anti-Pellino 1 antibody (ABIN7117275) specifically detects Pellino 1 in WB, ELISA and IP. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Pellino 1 antibody (ABIN7117275)

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-Pellino 1 Antibody

Purpose: PELI1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: pellino homolog 1(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Pellino 1

Target: Pellino 1 (PELI1) (Pellino E3 Ubiquitin Protein Ligase 1 (PELI1))

Alternative Name: PELI1

Background:

Synonyms: E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1)|Pellino-related intracellular-signaling molecule|RING-type E3 ubiquitin transferase pellino homolog 1|PELI1|PRISM

Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.

Molecular Weight: 46 kDa

Gene ID: 57162

UniProt: Q96FA3

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades