PHF20
Reactivity: Human
WB, IHC, ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
WB: 1:500-1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
PHF20
(PHD Finger Protein 20 (PHF20))
Alternative Name
PHF20
Background
Synonyms:C20orf104, GLEA2, Glioma expressed antigen 2, HCA58, Novel zinc finger protein, NZF, PHD finger protein 20, PHF20, Transcription factor TZP, TZP Background:Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation(H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes(By similarity). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.