PI4K2B antibody

Catalog No. ABIN7117401

The Rabbit Polyclonal anti-PI4K2B antibody (ABIN7117401) specifically detects PI4K2B in WB, IHC, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PI4K2B antibody (ABIN7117401)

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PI4K2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PI4K2B Antibody

Purpose: PI4K2B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: phosphatidylinositol 4-kinase type 2 beta

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PI4K2B

Target: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Alternative Name: PI4K2B

Background:

Synonyms: Phosphatidylinositol 4-kinase type 2-beta|Phosphatidylinositol 4-kinase type II-beta (PI4KII-BETA)|PI4K2B

Background: Together with PI4K2A and the type III PI4Ks(PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol(PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate(PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate(InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

Molecular Weight: 50-54 kDa

Gene ID: 55300

UniProt: Q8TCG2

Pathways: Inositol Metabolic Process