Phospholipase C delta 3 antibody

Catalog No. ABIN7117483

This Rabbit Polyclonal antibody specifically detects Phospholipase C delta 3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Phospholipase C delta 3 antibody (ABIN7117483)

Target: Phospholipase C delta 3 (PLCd3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase C delta 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Phospholipase C delta 3 Antibody

Purpose: PLCD3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: phospholipase C, delta 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Phospholipase C delta 3

Target: Phospholipase C delta 3 (PLCd3)

Alternative Name: PLCD3

Background:

Synonyms: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3|Phosphoinositide phospholipase C-delta-3|Phospholipase C-delta-3 (PLC-delta-3)|PLCD3|KIAA1964

Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.

Molecular Weight: 85 kDa

Gene ID: 113026

UniProt: Q8N3E9

Pathways: WNT Signaling