PIH1D1 antibody

Catalog No. ABIN7117531

This Rabbit Polyclonal antibody specifically detects PIH1D1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PIH1D1 antibody (ABIN7117531)

Target: PIH1D1 (PIH1 Domain Containing 1 (PIH1D1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIH1D1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PIH1D1 Antibody

Purpose: PIH1D1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PIH1 domain containing 1

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PIH1D1

Target: PIH1D1 (PIH1 Domain Containing 1 (PIH1D1))

Alternative Name: PIH1D1

Background:

Synonyms: PIH1 domain-containing protein 1|Nucleolar protein 17 homolog|PIH1D1|NOP17

Background: Involved in the assembly of C/D box small nucleolar ribonucleoprotein(snoRNP) particles(PubMed:17636026). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre-rRNA transcription(PubMed:22368283, PubMed:24036451). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1(PubMed:20864032). Positively regulates the assembly and activity of the mTORC1 complex(PubMed:24036451).

Molecular Weight: 32-40 kDa

Gene ID: 55011

UniProt: Q9NWS0