PVRIG antibody

Catalog No. ABIN7117614

This anti-PVRIG antibody is a Rabbit Polyclonal antibody detecting PVRIG in ELISA, WB and IHC. Suitable for Human.

Quick Overview for PVRIG antibody (ABIN7117614)

Target: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRIG antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PVRIG Antibody

Purpose: PVRIG antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: poliovirus receptor related immunoglobulin domain containing

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PVRIG

Target: PVRIG (Poliovirus Receptor-Related Immunoglobulin Domain Containing (PVRIG))

Alternative Name: PVRIG

Background:

Synonyms: Transmembrane protein PVRIG|CD112 receptor (CD112R)|Poliovirus receptor-related immunoglobulin domain-containing protein|PVRIG|C7orf15

Background: Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.

Molecular Weight: 34 kDa

Gene ID: 79037

UniProt: Q6DKI7