PHC2 antibody

Catalog No. ABIN7117653

The Rabbit Polyclonal anti-PHC2 antibody (ABIN7117653) specifically detects PHC2 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PHC2 antibody (ABIN7117653)

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-PHC2 Antibody

Purpose: PHC2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polyhomeotic homolog 2(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PHC2

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Alternative Name: PHC2

Background:

Synonyms: Polyhomeotic-like protein 2 (hPH2)|Early development regulatory protein 2|PHC2|EDR2|PH2

Background: Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 40 kDa

Gene ID: 1912

UniProt: Q8IXK0