POLG2 antibody

Catalog No. ABIN7117661

The Rabbit Polyclonal anti-POLG2 antibody has been validated for IHC, ELISA, WB and IF. It is suitable to detect POLG2 in samples from Human, Mouse and Rat.

Quick Overview for POLG2 antibody (ABIN7117661)

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-POLG2 Antibody

Purpose: POLG2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase (DNA directed), gamma 2, accessory subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLG2

Target: POLG2 (Polymerase (DNA Directed), gamma 2, Accessory Subunit (POLG2))

Alternative Name: POLG2

Background:

Synonyms: DNA polymerase subunit gamma-2, mitochondrial|DNA polymerase gamma accessory 55 kDa subunit (p55)|Mitochondrial DNA polymerase accessory subunit|MtPolB|PolG-beta|POLG2|MTPOLB

Background: This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Molecular Weight: 55 kDa

Gene ID: 11232

UniProt: Q9UHN1