POLR1C antibody

Catalog No. ABIN7117667

The Rabbit Polyclonal anti-POLR1C antibody has been validated for WB, ELISA and IHC. It is suitable to detect POLR1C in samples from Human, Mouse and Rat.

Quick Overview for POLR1C antibody (ABIN7117667)

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-POLR1C Antibody

Purpose: POLR1C antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) I polypeptide C, 30kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLR1C

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Alternative Name: POLR1C

Background:

Synonyms: DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C, RNA polymerases I and III subunit AC1)|AC40|DNA-directed RNA polymerases I and III 40 kDa polypeptide (RPA40)|RPA39|RPC40|POLR1C|POLR1E

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft(By similarity).

Molecular Weight: 39 kDa

Gene ID: 9533

UniProt: O15160