POLR2L antibody

Catalog No. ABIN7117678

This Rabbit Polyclonal antibody specifically detects POLR2L in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for POLR2L antibody (ABIN7117678)

Target: POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2L antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLR2L Antibody

Purpose: POLR2L antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) II(DNA directed) polypeptide L, 7.6kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLR2L

Target: POLR2L (Polymerase (RNA) II (DNA Directed) Polypeptide L, 7.6kDa (POLR2L))

Alternative Name: POLR2L

Background:

Synonyms: DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5)|DNA-directed RNA polymerase III subunit L|RNA polymerase II 7.6 kDa subunit (RPB7.6)|RPB10 homolog|POLR2L

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft(By similarity).

Molecular Weight: 8 kDa

Gene ID: 5441

UniProt: P62875

Pathways: Regulatory RNA Pathways