PRELID1 antibody

Catalog No. ABIN7117763

The Rabbit Polyclonal anti-PRELID1 antibody has been validated for ELISA and IHC. It is suitable to detect PRELID1 in samples from Human, Mouse and Rat.

Quick Overview for PRELID1 antibody (ABIN7117763)

Target: PRELID1 (PRELI Domain Containing 1 (PRELID1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRELID1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PRELID1 Antibody

Purpose: PRELID1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PRELI domain containing 1

Isotype: IgG

Application Details

Application Notes: IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PRELID1

Target: PRELID1 (PRELI Domain Containing 1 (PRELID1))

Alternative Name: PRELID1

Background:

Synonyms: PRELI domain-containing protein 1, mitochondrial|25 kDa protein of relevant evolutionary and lymphoid interest|Px19-like protein|PRELID1|PRELI

Background: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs.

Molecular Weight: 25 kDa

Gene ID: 27166

UniProt: Q9Y255