PREB antibody (AA 11-200)

Catalog No. ABIN7117807

This Rabbit Polyclonal antibody specifically detects PREB in ELISA, WB, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for PREB antibody (AA 11-200) (ABIN7117807)

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PREB Antibody

Binding Specificity: AA 11-200

Purpose: PREB antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 11-200aa

Immunogen: prolactin regulatory element binding

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB

Background:

Synonyms: Prolactin regulatory element-binding protein|Mammalian guanine nucleotide exchange factor mSec12|PREB|SEC12

Background: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene(PRL) promoter and seems to activate transcription.

Molecular Weight: 45 kDa

Gene ID: 10113

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling