PRSS50
Reactivity: Human
Host: Rabbit
Polyclonal
Biotin
Application Notes
WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target
PRSS50
(Protease, serine, 50 (PRSS50))
Alternative Name
TSP50
Background
Synonyms:Cancer/testis antigen 20, CT20, PRSS50, Serine protease 50, testes protease 50, TSP50 Background:TSP50(Testis-specific protease-like protein 50) is also named as PRSS50, CT20 and belongs to the peptidase S1 family. It can enhance the expression of NFKB target genes involved in cell proliferation, and promotes cell proliferation, at least partially, through activation of the NFKB signalling pathway(PMID:21385156). There are two protein bands of 37 kDa and 43 kDa to be detected in human testes that the the difference is most likely caused by posttranslational proteolytic cleavage(PMID:11782390). The full length protein has a signal peptide with 39 amino acids and two glycosylation sites.