PACSIN2 antibody

Catalog No. ABIN7117946

The Rabbit Polyclonal anti-PACSIN2 antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect PACSIN2 in samples from Human and Mouse.

Quick Overview for PACSIN2 antibody (ABIN7117946)

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACSIN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-PACSIN2 Antibody

Purpose: PACSIN2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein kinase C and casein kinase substrate in neurons 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PACSIN2

Target: PACSIN2 (Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2))

Alternative Name: PACSIN2

Background:

Synonyms: Protein kinase C and casein kinase substrate in neurons protein 2|Syndapin-2|Syndapin-II (SdpII)|PACSIN2

Background: Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Molecular Weight: 60-65 kDa

Gene ID: 11252

UniProt: Q9UNF0