PACSIN3 antibody

Catalog No. ABIN7117947

The Rabbit Polyclonal anti-PACSIN3 antibody (ABIN7117947) specifically detects PACSIN3 in WB, ELISA, IHC, FACS and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PACSIN3 antibody (ABIN7117947)

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PACSIN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-PACSIN3 Antibody

Purpose: PACSIN3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein kinase C and casein kinase substrate in neurons 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PACSIN3

Target: PACSIN3 (Protein Kinase C and Casein Kinase Substrate in Neurons 3 (PACSIN3))

Alternative Name: PACSIN3

Background:

Synonyms: Protein kinase C and casein kinase substrate in neurons protein 3|SH3 domain-containing protein 6511|PACSIN3

Background: Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity(By similarity).

Molecular Weight: 48 kDa

Gene ID: 29763

UniProt: Q9UKS6