PRKAA2 antibody

Catalog No. ABIN7117965

This anti-PRKAA2 antibody is a Rabbit Polyclonal antibody detecting PRKAA2 in WB, ELISA, IHC, IF and IP. Suitable for Human, Mouse and Rat.

Quick Overview for PRKAA2 antibody (ABIN7117965)

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-PRKAA2 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein kinase, AMP-activated, alpha 2 catalytic subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000, IHC: 1:20-1:200, IF: 1:10-1:100, IP:1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PRKAA2

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Alternative Name: AMPK alpha 2

Background: Synonyms:AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, PRKAA, PRKAA2 Background:PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).

Molecular Weight: 62 kDa

Gene ID: 5563

UniProt: P54646

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effect