POFUT2 antibody

Catalog No. ABIN7117982

The Rabbit Polyclonal anti-POFUT2 antibody has been validated for WB and ELISA. It is suitable to detect POFUT2 in samples from Human, Mouse and Rat.

Quick Overview for POFUT2 antibody (ABIN7117982)

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POFUT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POFUT2 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein O-fucosyltransferase 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for POFUT2

Target: POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Alternative Name: POFUT2

Background: Synonyms:C21orf80, FUT13, KIAA0958 Background:Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.

Molecular Weight: 49 kDa,50 kDa

Gene ID: 23275

UniProt: Q9Y2G5