PTPRA antibody

Catalog No. ABIN7118064

The Rabbit Polyclonal anti-PTPRA antibody (ABIN7118064) specifically detects PTPRA in WB, ELISA and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for PTPRA antibody (ABIN7118064)

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PTPRA Antibody

Purpose: PTPRA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: protein tyrosine phosphatase, receptor type, A

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PTPRA

Target: PTPRA (Protein tyrosine Phosphatase, Receptor Type, A (PTPRA))

Alternative Name: PTPRA

Background:

Synonyms: Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha, R-PTP-alpha)|PTPRA|PTPA|PTPRL2

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Molecular Weight: 70 kDa

Gene ID: 5786

UniProt: P18433